Naphthol AS-MX phosphate

MedChem Express

Naphthol AS-MX phosphate [1596-56-1]

5

1596-56-1

Research Use Only

99.50

C19H18NO5P

371.32

Naphthol AS-MX phosphate (NASTRp) is a small molecule inhibitor of the CREB (cyclic adenosine phosphate reaction element binding protein)- CBP (CREB binding protein) transcription factor complex. Naphthol AS-MX phosphate shows antitumor activity against lung cancer cells, inhibiting tumor cell proliferation ( IC 50 =3.701 micromol/L), colony formation, and anchored independent growth in soft AGAR. Naphthol AS-MX phosphate can be used in the study of KRAS mutated lung cancer, especially for KRAS mutated lung cancer with poor chemotherapy resistance and prognosis [1] .

O=C(C1=C(OP(O)(O)=O)C=C2C=CC=CC2=C1)NC3=CC=C(C)C=C3C

2°C to 8°C

12352200