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Naratriptan (hydrochloride)

HY-B0197A
MedChem Express
CAS Number143388-64-1
Product group Chemicals
Estimated Purity99.91
Molecular Weight371.93
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Naratriptan (hydrochloride) [143388-64-1]
  • Delivery Days Customer
    10
  • CAS Number
    143388-64-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.91
  • Molecular Formula
    C17H26ClN3O2S
  • Molecular Weight
    371.93
  • Scientific Description
    Naratriptan (GR-85548A) hydrochloride is a selective 5-HT1B/1D receptor agonist. Naratriptan hydrochloride is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC50=0.11 microM for dog basilar artery). Naratriptan hydrochloride also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan hydrochloride is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms[1][2][3][4].
  • SMILES
    O=S(CCC1=CC2=C(NC=C2C3CCN(C)CC3)C=C1)(NC)=O.Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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