Narlaprevir

MedChem Express

Narlaprevir [865466-24-6]

10

865466-24-6

Research Use Only

98.15

C36H61N5O7S

707.96

Narlaprevir (SCH 900518) is a selective and orally bioavailable NS3 protease inhibitor with a K i value of 6 nM and an EC 90 value of 40 nM [1] . Narlaprevir also inhibits the HCV nonstructural protein 3 serine protease [2] . Narlaprevir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 2.3 microM [3] .

O=S(CC1(NC(N[C@H](C(N2[C@@H]([C@@]3([H])C(C)([C@]3(C2)[H])C)C(N[C@H](C(C(NC4CC4)=O)=O)CCCC)=O)=O)C(C)(C)C)=O)CCCCC1)(C(C)(C)C)=O

-20°C,2°C to 8°C

12352200