Nav1.1 activator 1

MedChem Express

Nav1.1 activator 1 [2332897-85-3]

10

2332897-85-3

Research Use Only

99.89

C24H23F3N4O

440.46

Nav1.1 activator 1 (compound 4), a highly potent Nav1.1 activator with BBB penetration, increases decay time constant (tau) of Nav1.1 currents at 0.03 microM along with significant selectivity against Nav1.2, Nav1.5, and Nav1.6[1].

O=C(C1=C(C2=CC(F)=CC=C2F)C=CN=C1N3C[C@@H](F)CC3)NC4=CC=C(C(C)C)N=C4

-20°C,2°C to 8°C

12352200