NBL1 antibody [7P12]

GeneTex

NBL1 antibody [7P12]

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

7P12

500 ug/ml

Unconjugated

NBL1

NBL1, DAN family BMP antagonist

D1S1733E; DAN; DAN domain family member 1; DAND1; differential screening-selected gene aberrant in neuroblastoma; NB; neuroblastoma 1, DAN family BMP antagonist; neuroblastoma candidate region, suppression of tumorigenicity 1; neuroblastoma suppressor of tumorigenicity 1; NO3

Mouse

IgG2

Neuroblastoma suppressor of tumorigenicity 1

This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]

Human

-20°C or -80°C,2°C to 8°C

12352203