NC1153 [150661-91-9]
HY-115464
CAS Number150661-91-9
Product group Chemicals
Molecular Weight369.41
Overview
- SupplierMedChem Express
- Product NameNC1153 [150661-91-9]
- Delivery Days Customer9
- CAS Number150661-91-9
- CertificationResearch Use Only
- Molecular FormulaC18H38Cl2N2O
- Molecular Weight369.41
- Scientific DescriptionNC1153 is a Mannich base with the activity to block IL-2-induced JAK3 activation and its downstream substrate STAT5a/b. NC1153 effectively prolongs the survival of kidney transplants in MHC/non-MHC mismatched rats. NC1153 promotes long-term graft survival and includes multiple toxicity protection for recipients. NC1153 combined with cyclosporine A (CsA) can synergistically prolong graft survival without producing nephrotoxicity, myelotoxicity or lipotoxicity[1].
- SMILESO=C1C(CN(C)C)CCCCCCCCCC1CN(C)C.Cl.Cl
- UNSPSC12352200