NCAM / CD56 Antibody Cocktail

Biorbyt

NCAM / CD56 Antibody Cocktail

16

The optimal dilution of the CD56 antibody for each application should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Flow Cytometry, ImmunoFluorescence, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT FACS, IF, IHC-P

Research Use Only

Monoclonal

123C3.D5 + 123A8

Unconjugated

NCAM1

neural cell adhesion molecule 1

antigen recognized by monoclonal antibody 5.1H11; CD56; MSK39; NCAM; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM

Mouse

IgG1

Neural cell adhesion molecule 1

Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

-20°C,2°C to 8°C

12352203