Bio-Connect

NCB-0846

HY-100830
MedChem Express
CAS Number1792999-26-8
Product group Chemicals
Estimated Purity99.61
Molecular Weight375.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NCB-0846 [1792999-26-8]
  • Delivery Days Customer
    10
  • CAS Number
    1792999-26-8
  • Estimated Purity
    99.61
  • Molecular Formula
    C21H21N5O2
  • Molecular Weight
    375.42
  • Scientific Description
    NCB-0846 is an orally active, selective inhibitor for Wnt , that inhibits Traf2- and Nck-interacting kinase ( TNIK ) with an IC 50 of 21 nM. NCB-0846 blocks TGF-beta signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation [1] [2] .
  • SMILES
    O[C@@H](CC1)CC[C@@H]1OC2=CC=CC(C=N3)=C2N=C3NC4=CC=C(N=CN5)C5=C4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200