NCB-0846
HY-100830
CAS Number1792999-26-8
Product group Chemicals
Estimated Purity99.61
Molecular Weight375.42
Overview
- SupplierMedChem Express
- Product NameNCB-0846 [1792999-26-8]
- Delivery Days Customer10
- CAS Number1792999-26-8
- CertificationResearch Use Only
- Estimated Purity99.61
- Molecular FormulaC21H21N5O2
- Molecular Weight375.42
- Scientific DescriptionNCB-0846 is an orally active, selective inhibitor for Wnt , that inhibits Traf2- and Nck-interacting kinase ( TNIK ) with an IC 50 of 21 nM. NCB-0846 blocks TGF-beta signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation [1] [2] .
- SMILESO[C@@H](CC1)CC[C@@H]1OC2=CC=CC(C=N3)=C2N=C3NC4=CC=C(N=CN5)C5=C4
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200