NCGC00378430

MedChem Express

NCGC00378430 [920650-00-6]

10

920650-00-6

Research Use Only

99.58

C22H23N3O5S

441.50

NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor. NCGC00378430 partially reverses transcriptional and metabolic profiles mediated by SIX1 overexpression and reverses SIX1-induced TGF-beta signaling and epithelial-mesenchymal transition (EMT). NCGC00378430 inhibits SIX1-mediated breast cancer metastasis in a mouse model [1] .

O=C(NC1=CC=C(OC)C(S(=O)(N2CCOCC2)=O)=C1)C3=CC=CC(N4C=CC=C4)=C3

-20°C,2°C to 8°C

12352200