
Western blot All lanes: Cytoplasmic protein NCK1 antibody at 4ug/ml + Rat liver tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 43, 36 kDa Observed band size: 43 kDa
NCK1 Antibody
CSB-PA015530DSR2HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetNCK1
Overview
- SupplierCusabio
- Product NameNCK1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4690
- Target nameNCK1
- Target descriptionNCK adaptor protein 1
- Target synonymscytoplasmic protein NCK1; melanoma NCK protein; NCK; NCK tyrosine kinase; nck-1; NCKalpha; non-catalytic region of tyrosine kinase; SH2/SH3 adaptor protein NCK-alpha
- HostRabbit
- IsotypeIgG
- Protein IDP16333
- Protein NameCytoplasmic protein NCK1
- Scientific DescriptionAdapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203