NCR2 Polyclonal Antibody

Reddot Biotech

NCR2 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.6 mg/ml

Unconjugated

NCR2

natural cytotoxicity triggering receptor 2

CD336; dJ149M18.1; LY95; lymphocyte antigen 95 (activating NK-receptor; NK-p44); lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44); natural cytotoxicity triggering receptor 2; natural killer cell p44-related protein; NK cell activating receptor (NKp44); NK cell-activating receptor; NKP44; NK-p44

Rabbit

IgG

Natural cytotoxicity triggering receptor 2is aproteinthat in humans is encoded by theNCR2gene. NCR2 has also been designated asCD336(cluster of differentiation336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.

Human

-20°C

12352203