NCT-502 [1542213-00-2]

MedChem Express

NCT-502 [1542213-00-2]

10

1542213-00-2

Research Use Only

98.59

C18H20F3N5S

395.45

NCT-502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC50 of 3.7 microM against PHGDH[1].

S=C(NC1=NC(C)=CC(C)=C1)N2CCN(CC2)C3=NC=C(C=C3)C(F)(F)F

-20°C,2°C to 8°C

12352200