NCT-505 [2231079-74-4]

MedChem Express

NCT-505 [2231079-74-4]

10

2231079-74-4

Research Use Only

99.37

C27H28FN5O3S

521.61

NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM, and weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 (IC50s, >57, 22.8, 20.1, >57 microM).

N#CC1(C2=CC=CC=C2)CCN(C3=C(C(N4CCN(S(=O)(C)=O)CC4)=O)C=NC5=CC=C(F)C=C35)CC1

-20°C,2°C to 8°C

12352200