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NCT-58 [2411429-33-7]

NCT-58 [2411429-33-7]

T9996
TargetMol Chemicals
CAS Number2411429-33-7
DownloadMSDS
Product group Chemicals
Estimated Purity98.75%
Molecular Weight466.57
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    NCT-58 [2411429-33-7]
  • Delivery Days Customer
    9
  • CAS Number
    2411429-33-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    NCT-58
  • Estimated Purity
    98.75%
  • Molecular Formula
    C27H34N2O5
  • Molecular Weight
    466.57
  • Scientific Description
    NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits anti-tumor activity via the simultaneous downregulation of HER family members as well as inhibition of Akt phosphorylation. NCT-58 kills Trastuzumab-resistant breast cancer stem-like cells. NCT-58 induces apoptosis in HER2-positive breast cancer cells.
  • Shelf life instruction
    3 years
  • SMILES
    COc1cc(NC(=O)c2ccc3OC(C)(C)C=Cc3c2OC)ccc1OCCC1CCCCN1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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