ND-2158 [1388896-07-8]
HY-120041
CAS Number1388896-07-8
Product group Chemicals
Molecular Weight446.56
Overview
- SupplierMedChem Express
- Product NameND-2158 [1388896-07-8]
- Delivery Days Customer14
- CAS Number1388896-07-8
- CertificationResearch Use Only
- Molecular FormulaC22H30N4O4S
- Molecular Weight446.56
- Scientific DescriptionND-2158 is a competitive IRAK4 inhibitor, with the Ki of 1.3 nM. ND-2158 suppresses LPS-induced TNF production in human white blood cells, alleviated collagen-induced arthritis, and blocked gout formation in mouse models. ND-2158 has antitumor activity in vivo[1].
- SMILESO=C(N)[C@@H](O)C[C@H]1CCC2=C1C3=C(O[C@@H]4CC[C@@H](N5CCOCC5)CC4)N=CN=C3S2
- UNSPSC12352200