
IHC image of CSB-PA859515LA01HU diluted at 1:400 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
NDN Antibody
CSB-PA859515LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNDN
Overview
- SupplierCusabio
- Product NameNDN Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4692
- Target nameNDN
- Target descriptionnecdin, MAGE family member
- Target synonymsHsT16328; necdin; necdin homolog; necdin, melanoma antigen (MAGE) family member; necdin-like protein; Prader-Willi syndrome chromosome region; PWCR
- HostRabbit
- IsotypeIgG
- Protein IDQ99608
- Protein NameNecdin
- Scientific DescriptionGrowth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161