NDNA3
HY-149432
Overview
- SupplierMedChem Express
- Product NameNDNA3
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC28H32N2O3S
- Molecular Weight476.63
- Scientific DescriptionNDNA3 (compound 14) is a selective inhibitor of Hsp90alpha (IC50: 0.51 microM). NDNA3 is a permanently charged analog with low membrane permeability and low toxicity to Ovcar-8 (IC50: 12.66 microM) and MCF-10A (IC50: 11.72 microM) cells. NDNA3 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90alpha-dependent client proteins[1].
- SMILESCN(C)CCCOC1=CC2=C(CN(C(C3=CC=C(O)C(SC4=CC=C(C)C(C)=C4)=C3)=O)C2)C=C1
- UNSPSC12131703