Bio-Connect

NDNA3

HY-149432
MedChem Express
Molecular Weight476.63
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NDNA3
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C28H32N2O3S
  • Molecular Weight
    476.63
  • Scientific Description
    NDNA3 (compound 14) is a selective inhibitor of Hsp90alpha (IC50: 0.51 microM). NDNA3 is a permanently charged analog with low membrane permeability and low toxicity to Ovcar-8 (IC50: 12.66 microM) and MCF-10A (IC50: 11.72 microM) cells. NDNA3 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90alpha-dependent client proteins[1].
  • SMILES
    CN(C)CCCOC1=CC2=C(CN(C(C3=CC=C(O)C(SC4=CC=C(C)C(C)=C4)=C3)=O)C2)C=C1
  • UNSPSC
    12131703