NDNA4
HY-149431
Overview
- SupplierMedChem Express
- Product NameNDNA4
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC31H35F3N2O5S
- Molecular Weight604.68
- Scientific DescriptionNDNA4 (compound 17) is a selective inhibitor of Hsp90alpha (IC50: 0.34 microM). NDNA4 is a permanently charged analog with low membrane permeability and low cytotoxicity against Ovcar-8 and MCF-10A ((IC50 >100 microM)). NDNA4 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90alpha-dependent client proteins[1].
- SMILESC[N+](C)(C)CCCOC1=CC2=C(CN(C(C3=CC=C(O)C(SC4=CC=C(C)C(C)=C4)=C3)=O)C2)C=C1.O=C([O-])C(F)(F)F
- UNSPSC12131703