Bio-Connect

NDNA4

HY-149431
MedChem Express
Molecular Weight604.68
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NDNA4
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C31H35F3N2O5S
  • Molecular Weight
    604.68
  • Scientific Description
    NDNA4 (compound 17) is a selective inhibitor of Hsp90alpha (IC50: 0.34 microM). NDNA4 is a permanently charged analog with low membrane permeability and low cytotoxicity against Ovcar-8 and MCF-10A ((IC50 >100 microM)). NDNA4 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90alpha-dependent client proteins[1].
  • SMILES
    C[N+](C)(C)CCCOC1=CC2=C(CN(C(C3=CC=C(O)C(SC4=CC=C(C)C(C)=C4)=C3)=O)C2)C=C1.O=C([O-])C(F)(F)F
  • UNSPSC
    12131703