NDST1 Antibody

Cusabio

NDST1 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

NDST1

N-deacetylase and N-sulfotransferase 1

HSST, MRT46, NST1, bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, HSNST 1, N-Deacetylase-N-sulfotransferase 1, N-HSST 1, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1, N-deacetylase/N-sulfotransferase 1, N-heparan sulfate sulfotransferase 1, NDST-1, [Heparan sulfate]-glucosamine N-sulfotransferase 1, glucosaminyl N-deacetylase/N-sulfotransferase 1, heparan sulfate-N-deacetylase/N-sulfotransferase, heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase 1

Rabbit

IgG

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.

Human

-20°C or -80°C

41116161