NDUFS1 antibody
GTX105270
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNDUFS1
Overview
- SupplierGeneTex
- Product NameNDUFS1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID4719
- Target nameNDUFS1
- Target descriptionNADH:ubiquinone oxidoreductase core subunit S1
- Target synonymsCI-75k; CI-75Kd; complex I 75kDa subunit; complex I, mitochondrial respiratory chain, 75-kD subunit; MC1DN5; mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase); NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; PRO1304
- HostRabbit
- IsotypeIgG
- Protein IDP28331
- Protein NameNADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- Scientific DescriptionThe protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy. Wu Z et al., 2018 Jul 3, Cell MetabRead more
- Mitochondrial proteomics with siRNA knockdown to reveal ACAT1 and MDH2 in the development of doxorubicin-resistant uterine cancer. Lo YW et al., 2015 Apr, J Cell Mol MedRead more