Bio-Connect

NE58018 [105462-23-5]

HY-117012
MedChem Express
CAS Number105462-23-5
Product group Chemicals
Molecular Weight283.11
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NE58018 [105462-23-5]
  • Delivery Days Customer
    9
  • CAS Number
    105462-23-5
  • Certification
    Research Use Only
  • Molecular Formula
    C7H11NO7P2
  • Molecular Weight
    283.11
  • Scientific Description
    NE58018 is a compound with bone resorption inhibitory activity. NE58018 exerts its effect by affecting the action of Farnesyl pyrophosphate synthase (FPPS). The structural features of NE58018 combined with aminophosphonates significantly enhance its inhibitory activity. NE58018 affects the roles of Thr201 and Tyr204 residues in substrate binding and catalysis. The interaction of NE58018 enhances the inhibitory effect on the target enzyme[1].
  • SMILES
    OC([P](O)(O)=O)([P](O)(O)=O)CC1=CC=CC=N1
  • UNSPSC
    12352200