Nebicapone [274925-86-9]

MedChem Express

Nebicapone [274925-86-9]

10

274925-86-9

Research Use Only

99.89

C14H11NO5

273.24

Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinsons disease[1].

O=C(C1=CC([N+]([O-])=O)=C(O)C(O)=C1)CC2=CC=CC=C2

2°C to 8°C

12352200