Neflamapimod

MedChem Express

Neflamapimod [209410-46-8]

10

209410-46-8

Research Use Only

99.32

C19H9Cl2F2N3OS

436.26

Neflamapimod (VX-745) is a potent, blood-brain barrier penetrant, highly selective inhibitor of p38alpha inhibitor with an IC 50 for p38alpha of 10 nM and for p38beta of 220 nM. Neflamapimod (VX-745) possesses anti-inflammatory activity.

O=C1N=CN(C(C=C2)=C1C3=C(Cl)C=CC=C3Cl)N=C2SC4=CC=C(F)C=C4F

-20°C,2°C to 8°C

12352200