Nemtabrutinib [2095393-15-8]

MedChem Express

Nemtabrutinib [2095393-15-8]

10

2095393-15-8

Research Use Only

99.32

C25H23ClN4O4

478.93

Nemtabrutinib (ARQ 531) is a reversible non-covalent and orally active inhibitor of Brutons Tyrosine Kinase (BTK), with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively.

O=C(C1=C(C=C(OC2=CC=CC=C2)C=C1)Cl)C3=CNC4=NC=NC(N[C@@H]5CC[C@@H](CO)OC5)=C34

-20°C,2°C to 8°C

12352200