IHC image of CSB-PA892354NA01HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
NENF Antibody
CSB-PA892354NA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNENF
Overview
- SupplierCusabio
- Product NameNENF Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID29937
- Target nameNENF
- Target descriptionneudesin neurotrophic factor
- Target synonymscell growth-inhibiting protein 47; cell immortalization-related protein 2; CIR2; neudesin; neuron-derived neurotrophic factor; SCIRP10; SCIRP10-related protein; secreted protein of unknown function; Spinal cord injury related protein 10; SPUF
- HostRabbit
- IsotypeIgG
- Protein IDQ9UMX5
- Protein NameNeudesin
- Scientific DescriptionActs as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). Plays a role in the human tumorigenesis (PubMed:22748190).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203