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NEO2734 [2081072-29-7]

NEO2734 [2081072-29-7]

T8658
TargetMol Chemicals
CAS Number2081072-29-7
Product group Chemicals
Estimated Purity98.56%
Molecular Weight435.44
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    NEO2734 [2081072-29-7]
  • Delivery Days Customer
    9
  • CAS Number
    2081072-29-7
  • Certification
    Research Use Only
  • Chemical Name
    NEO2734
  • Estimated Purity
    98.56%
  • Molecular Formula
    C22H24F3N3O3
  • Molecular Weight
    435.44
  • Scientific Description
    NEO2734 (EP31670) is an orally active, selective inhibitor of p300/CBP and BET bromodomains, with an IC50 of less than 30 nM for both targets.
  • Shelf life instruction
    3 years
  • SMILES
    Cc1cc(cn(C)c1=O)-c1ccc2nc(C3CCOCC3)n(CCOC(F)(F)F)c2c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Yan Y, Ma J, Wang D, et al. The novel BET-CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild-type prostate cancer. EMBO Mol Med. 2019,11(11):e10659. doi: 10.15252/emmm.201910659
    Read this paper