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Neoandrographolide [27215-14-1]

HY-N0721
MedChem Express
CAS Number27215-14-1
Product group Chemicals
Estimated Purity99.41
Molecular Weight480.59
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Neoandrographolide [27215-14-1]
  • Delivery Days Customer
    10
  • CAS Number
    27215-14-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.41
  • Molecular Formula
    C26H40O8
  • Molecular Weight
    480.59
  • Scientific Description
    Neoandrographolide is a diterpenoid compound isolated from Andrographis paniculata. Neoandrographolide inhibits osteoclasts differentiation and bone resorption through inhibition of MAPK/NF-kappaB/PI3K/AKT/GSK3beta/PPAR/CAMK signaling pathway. Neoandrographolide inhibits apoptosis in rat embryonic ventricular cardiomyocytes. Neoandrographolide inhibits iNOS and the generation of ROS, activates eNOS, exhibiting anti-inflammatory and hypolipidemic activity[1][2][3][4][5].
  • SMILES
    C[C@@]([C@@H]1CCC2=CCOC2=O)(CCC3)[C@@](CCC1=C)([H])[C@]3(C)CO[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12131703