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Nepicastat (hydrochloride)

HY-13289A
MedChem Express
CAS Number170151-24-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.48
Molecular Weight331.81
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Nepicastat (hydrochloride) [170151-24-3]
  • Delivery Days Customer
    10
  • CAS Number
    170151-24-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.48
  • Molecular Formula
    C14H16ClF2N3S
  • Molecular Weight
    331.81
  • Scientific Description
    Nepicastat hydrochloride (SYN-117 hydrochloride) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat hydrochloride produces concentration-dependent inhibition of bovine (IC50=8.5 nM) and human (IC50=9 nM) dopamine-beta-hydroxylase. Nepicastat hydrochloride can cross the blood-brain barrier (BBB)[1][2][3].
  • SMILES
    FC1=CC(F)=C2CC[C@@H](CC2=C1)N3C(CN)=CNC3=S.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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