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Neratinib maleate

ORB1944868
Biorbyt
CAS Number915942-22-2
Product group Chemicals
Estimated Purity99.64%
Molecular Weight673.11
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Neratinib maleate [915942-22-2]
  • Delivery Days Customer
    10
  • CAS Number
    915942-22-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.64%
  • Molecular Formula
    C34H33ClN6O7
  • Molecular Weight
    673.11
  • Scientific Description
    Neratinib maleate (HKI-272 maleate) is an irreversible, orally active and highly selective inhibitor of HER2 and EGFR with IC50 values of 59 nM and 92 nM, respectively.Neratinib maleate has antitumor activity and can be used to treat gastrointestinal, respiratory, genitourinary, and cutaneous and musculoskeletal diseases, and can be used to study breast and prostate cancer. used in the study of breast and prostate cancer.
  • SMILES
    OC(=O)\C=C/C(O)=O.CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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