Nerigliatin

MedChem Express

Nerigliatin [1245603-92-2]

10

1245603-92-2

Research Use Only

99.94

C22H20N6O4

432.43

Nerigliatin (PF-04937319) is a glucokinase activator ( GKA ) with EC 50 value of 154.4 microM, one of the most promising strategies for the treatment of type 2 diabetes mellitus [1] . Nerigliatin is designed to maintain glucose-lowering efficacy while mitigating the risk of hypoglycaemia observed with many other GKAs [2] .

O=C(C1=NC=C(OC2=C3C=C(C)OC3=CC(C(NC4=NC=C(C)N=C4)=O)=C2)C=N1)N(C)C

-20°C,2°C to 8°C

12352200