Neurobeachin antibody, C-term

GeneTex

Neurobeachin antibody, C-term

7

This antibody is expected to recognise isoform 1 (NP_056493.3) and isoform 2 (NP_001191126.1).

WB: 1-3microg/ml. IHC-P: 5-10microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

NBEA

neurobeachin

BCL8B; lysosomal-trafficking regulator 2; LYST2; NEDEGE; neurobeachin

Goat

IgG

Neurobeachin

This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203