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GTX60971 tested on tissue from human cerebral cortex, applying ultra thin sections using a technique called array tomography. (antibody: green, DAPI-stained nuclei: blue). The antibody labels NPY-positive processes in the neutrophil. Courtesy of Dr. Nancy ORourke, Stanford University.
GTX60971 tested on tissue from human cerebral cortex, applying ultra thin sections using a technique called array tomography. (antibody: green, DAPI-stained nuclei: blue). The antibody labels NPY-positive processes in the neutrophil. Courtesy of Dr. Nancy ORourke, Stanford University.
GTX60971 tested on tissue from human cerebral cortex, applying ultra thin sections using a technique called array tomography. (antibody: green, DAPI-stained nuclei: blue). The antibody labels NPY-positive processes in the neutrophil. Courtesy of Dr. Nancy ORourke, Stanford University.

Neuropeptide Y antibody [8]

GTX60971
GeneTex
ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNPY
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Overview

  • Supplier
    GeneTex
  • Product Name
    Neuropeptide Y antibody [8]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody binds full length human/rat Neuropeptide Y (NPY). Cross-reactivity with NPY (1-24) , NPY (18-36), PYY or PP was <0.2%.
  • Applications
    ImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    8
  • Conjugate
    Unconjugated
  • Gene ID4852
  • Target name
    NPY
  • Target description
    neuropeptide Y
  • Target synonyms
    prepro-neuropeptide Y; pro-neuropeptide Y; PYY4
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01303
  • Protein Name
    Pro-neuropeptide Y
  • Scientific Description
    This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Histological study on regional specificity of the mucosal nerve network in the rat large intestine.
    Read more
  • Upregulation of Mir342 in Diet-Induced Obesity Mouse and the Hypothalamic Appetite Control. Zhang D et al., 2021, Front Endocrinol (Lausanne)
    Read more