Neuroserpin blocking peptide

GeneTex

Neuroserpin blocking peptide

9

Research Use Only

SERPINI1

serpin family I member 1

HNS-S1, HNS-S2, PI12, neuroserpin, neuroserpin, PI-12, peptidase inhibitor 12, serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1, serpin I1, serpin peptidase inhibitor clade I member 1, serpin peptidase inhibitor, clade I (neuroserpin), member 1

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

41116100

Human