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Nevanimibe

HY-100399
MedChem Express
CAS Number133825-80-6
DownloadMSDS
Product group Chemicals
Molecular Weight421.62
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Nevanimibe [133825-80-6]
  • Delivery Days Customer
    5
  • CAS Number
    133825-80-6
  • Molecular Formula
    C27H39N3O
  • Molecular Weight
    421.62
  • Scientific Description
    Nevanimibe (PD-132301) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 ( ACAT1 ) inhibitor with an EC 50 of 9 nM. Nevanimibe inhibits ACAT2 with an EC 50 of 368 nM. Nevanimibe induces cell apoptosis and has the potential for adrenocortical cancer [1] .
  • SMILES
    O=C(NCC1(C2=CC=C(N(C)C)C=C2)CCCC1)NC3=C(C(C)C)C=CC=C3C(C)C
  • UNSPSC
    12352200