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NF-H antibody

GTX110065
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNEFH
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Overview

  • Supplier
    GeneTex
  • Product Name
    NF-H antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.71 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4744
  • Target name
    NEFH
  • Target description
    neurofilament heavy chain
  • Target synonyms
    200 kDa neurofilament protein; CMT2CC; neurofilament heavy polypeptide; neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; NFH; NF-H
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP12036
  • Protein Name
    Neurofilament heavy polypeptide
  • Scientific Description
    Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Ninjurin 1 mediates peripheral nerve regeneration through Schwann cell maturation of NG2-positive cells. Tomita Y et al., 2019 Nov 12, Biochem Biophys Res Commun
    Read more
  • Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosis. Pigna E et al., 2019 Feb, EBioMedicine
    Read more

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