NF-kappaB-IN-1 [1227098-15-8]

TargetMol Chemicals

NF-kappaB-IN-1 [1227098-15-8]

4

1227098-15-8

Chemical

Research Use Only

NF-kappaB-IN-1

99.29%

C31H30O8

530.57

NF-kappaB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-kappaB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-kappaB-IN-1 directly inhibits IKK to block NF-kappaB activation. NF-kappaB-IN-1 effectively inhibits the viability of lung cancer cells and attenuates the clonogenic activity of A549 cells.

3 years

COc1ccc(\C=C\C(=O)C(=Cc2ccc(O)c(OC)c2)C(=O)\C=C\c2ccc(OC)c(OC)c2)cc1OC

-20°C

51202000