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NFAT Inhibitor-2 [422546-87-0]

HY-W181102
MedChem Express
CAS Number422546-87-0
Product group Chemicals
Estimated Purity98.42
Molecular Weight446.47
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NFAT Inhibitor-2 [422546-87-0]
  • Delivery Days Customer
    10
  • CAS Number
    422546-87-0
  • Certification
    Research Use Only
  • Estimated Purity
    98.42
  • Molecular Formula
    C22H20F2N2O4S
  • Molecular Weight
    446.47
  • Scientific Description
    NFAT Inhibitor-2 is a potent inhibitor of calcineurin NFAT signalling. Calcineurin is a serine/threonine protein phosphatase regulated by Ca2+ and calmodulin. NFAT Inhibitor-2 has the potential for the research of inflammatory disease, an autoimmune disorder, a cardiovascular disease, a neurodegenerative disease, a disease occurring with uncontrolled cell proliferation and/or differentiation, an angiogenesis-related disease, an allergy, anaphylaxis and alopecia (extracted from patent WO2016207212A1, compound 17)[1].
  • SMILES
    O=C(NC1=CC=C(C)C(F)=C1)C2=CC=C(F)C(S(=O)(NCC3=CC=C(OC)C=C3)=O)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200