NFAT Inhibitor-2 [422546-87-0]
HY-W181102
CAS Number422546-87-0
Product group Chemicals
Estimated Purity98.42
Molecular Weight446.47
Overview
- SupplierMedChem Express
- Product NameNFAT Inhibitor-2 [422546-87-0]
- Delivery Days Customer10
- CAS Number422546-87-0
- CertificationResearch Use Only
- Estimated Purity98.42
- Molecular FormulaC22H20F2N2O4S
- Molecular Weight446.47
- Scientific DescriptionNFAT Inhibitor-2 is a potent inhibitor of calcineurin NFAT signalling. Calcineurin is a serine/threonine protein phosphatase regulated by Ca2+ and calmodulin. NFAT Inhibitor-2 has the potential for the research of inflammatory disease, an autoimmune disorder, a cardiovascular disease, a neurodegenerative disease, a disease occurring with uncontrolled cell proliferation and/or differentiation, an angiogenesis-related disease, an allergy, anaphylaxis and alopecia (extracted from patent WO2016207212A1, compound 17)[1].
- SMILESO=C(NC1=CC=C(C)C(F)=C1)C2=CC=C(F)C(S(=O)(NCC3=CC=C(OC)C=C3)=O)=C2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
![NFAT Inhibitor-2 [422546-87-0]](https://www.targetmol.com/group3/M00/02/7F/CgoaEWY7L5iED3vSAAAAAAVO5u0156.png)