NFKBID Polyclonal Antibody
RD77278A
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetNFKBID
Overview
- SupplierReddot Biotech
- Product NameNFKBID Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.4 mg/ml
- ConjugateUnconjugated
- Gene ID84807
- Target nameNFKBID
- Target descriptionNFKB inhibitor delta
- Target synonymsikappaBdelta; I-kappa-B-delta; IkappaBNS; ikB-delta; IkBNS; NF-kappa-B inhibitor delta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta; TA-NFKBH; T-cell activation NFKB-like protein
- HostRabbit
- IsotypeIgG
- Scientific DescriptionMay regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IkappaBNS, the nuclear IkappaB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IkappaBNS has been identified as a member of the IkappaB family of NF-kappaB inhibitors, which undergoes induction upon TCR signaling. IkappaBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203