NFKBID Polyclonal Antibody

Reddot Biotech

NFKBID Polyclonal Antibody

5

0.4 mg/ml

NFKBID

NFKB inhibitor delta

ikappaBdelta; I-kappa-B-delta; IkappaBNS; ikB-delta; IkBNS; NF-kappa-B inhibitor delta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta; TA-NFKBH; T-cell activation NFKB-like protein

May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IkappaBNS, the nuclear IkappaB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IkappaBNS has been identified as a member of the IkappaB family of NF-kappaB inhibitors, which undergoes induction upon TCR signaling. IkappaBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

-20°C

12352203