Bio-Connect

NGB 2904 [189060-98-8]

HY-12697
MedChem Express
CAS Number189060-98-8
Product group Chemicals
Estimated Purity98.28
Molecular Weight494.46
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NGB 2904 [189060-98-8]
  • Delivery Days Customer
    10
  • CAS Number
    189060-98-8
  • Certification
    Research Use Only
  • Estimated Purity
    98.28
  • Molecular Formula
    C28H29Cl2N3O
  • Molecular Weight
    494.46
  • Scientific Description
    NGB 2904 is a potent, selective, orally active and brain-penetrated antagonist of dopamine D3 receptor, with a Ki of 1.4 nM. NGB 2904 shows selectivity for D3 over D2, 5-HT2, alpha1, D4, D1 and D5 receptors (Kis=217, 223, 642, >5000, >10000 and >10000 nM, respectively). NGB 2904 antagonizes Quinpirole-stimulated mitogenesis[1][2].
  • SMILES
    O=C(C1=CC(CC2=C3C=CC=C2)=C3C=C1)NCCCCN4CCN(C5=CC=CC(Cl)=C5Cl)CC4
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200