NGFR, Mouse (HEK293, His)

MedChem Express

NGFR, Mouse (HEK293, His)

10

Research Use Only

97.30

Ngfr

nerve growth factor receptor (TNFR superfamily, member 16)

LNGFR, Tnfrsf16, p75, p75NGFR, p75NTR, tumor necrosis factor receptor superfamily member 16, NGF receptor, low affinity neurotrophin receptor p75NTR, low-affinity nerve growth factor receptor, low-affinity nerve growth factor receptor p75NGFR, low-affinity nerve growth factor receptor p75NGR, p75 neurotrophin receptor

Tumor necrosis factor receptor superfamily member 16

Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation[1]. NGF-NGFR cascade activates NF-kappaB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells[3]. NGFR Protein, Mouse (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 243 amino acids (M1-N243) and is produced in HEK293 cells.

-20°C

41116100

Mouse