NHE3-IN-3 [543734-50-5]
HY-151360
CAS Number543734-50-5
Product group Chemicals
Molecular Weight371.28
Overview
- SupplierMedChem Express
- Product NameNHE3-IN-3 [543734-50-5]
- Delivery Days Customer10
- CAS Number543734-50-5
- CertificationResearch Use Only
- Molecular FormulaC16H16Cl2N2O2S
- Molecular Weight371.28
- Scientific DescriptionNHE3-IN-3 (Compound 1) is a Na+/H+ exchanger isoform 3 (NHE3) inhibitor with pIC50 of 6.2 and 6.6 against human and rat NHE3, respectively. NHE3-IN-3 shows high (98%) oral bioavailability in Sprague-Dawley rats[1].
- SMILESCN1CC2=C(C(C1)C3=CC(S(N)(=O)=O)=CC=C3)C=C(C=C2Cl)Cl
- UNSPSC12131703