NHERF1 antibody [EBP-10]

GeneTex

NHERF1 antibody [EBP-10]

9

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

EBP-10

1 mg/ml

Unconjugated

NHERF1

NHERF family PDZ scaffold protein 1

EBP50, NHE-RF, NHERF, NHERF-1, NPHLOP2, SLC9A3R1, Na(+)/H(+) exchange regulatory cofactor NHE-RF1, Na(+)/H(+) exchange regulatory cofactor 1, Na+/H+ exchange regulatory co-factor, SLC9A3 regulator 1, ezrin-radixin-moesin binding phosphoprotein-50, regulatory cofactor of Na(+)/H(+) exchanger, solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1

Mouse

IgG2b

Na(+)/H(+) exchange regulatory cofactor NHE-RF1

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009]

Human

2°C to 8°C

12352203