NHERF1 antibody [EBP-10]
GTX29526
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetSLC9A3R1
Overview
- SupplierGeneTex
- Product NameNHERF1 antibody [EBP-10]
- Delivery Days Customer9
- Antibody SpecificityThis antibody reacts with NHERF1/EBP50 phosphoprotein of 50 kDa.
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDEBP-10
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9368
- Target nameSLC9A3R1
- Target descriptionSLC9A3 regulator 1
- Target synonymsEBP50; ezrin-radixin-moesin binding phosphoprotein-50; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Na+/H+ exchange regulatory co-factor; NHERF; NHERF1; NHERF-1; NPHLOP2; regulatory cofactor of Na(+)/H(+) exchanger; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
- HostMouse
- IsotypeIgG2b
- Scientific DescriptionThis gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203