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NHERF1 antibody [EBP-10]

Research Use Only
GTX29526
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetSLC9A3R1
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    NHERF1 antibody [EBP-10]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody reacts with NHERF1/EBP50 phosphoprotein of 50 kDa.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    EBP-10
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9368
  • Target name
    SLC9A3R1
  • Target description
    SLC9A3 regulator 1
  • Target synonyms
    EBP50; ezrin-radixin-moesin binding phosphoprotein-50; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Na+/H+ exchange regulatory co-factor; NHERF; NHERF1; NHERF-1; NPHLOP2; regulatory cofactor of Na(+)/H(+) exchanger; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
  • Host
    Mouse
  • Isotype
    IgG2b
  • Scientific Description
    This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203