NHWD-870 [2115742-03-3]

TargetMol Chemicals

NHWD-870 [2115742-03-3]

86

2115742-03-3

Chemical

Research Use Only

NHWD-870

C29H29N7O

491.59

NHWD-870 is an effective and selective inhibitor of BET family bromodomain only binding to BRD2, BRD3, BRD4 (IC50 = 2.7 nM), and BRDT. NHWD-870 exhibits potent anti-tumor efficacies and suppresses cancer cell-macrophage interaction through the increase of tumor apoptosis and inhibition of tumor proliferation.

3 years

Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc3n(C)ncc3cc21

-20°C

12352200