NI-42 [1884640-99-6]

TargetMol Chemicals

NI-42 [1884640-99-6]

4

1884640-99-6

Chemical

Research Use Only

NI-42

99.17%

C18H15N3O3S

353.39

NI-42 is a structurally orthogonal chemical probe for the BRPFs and is biased. It effective inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM). It also has excellent selectivity over nonclass IV BRD proteins.

3 years

Cc1cc2cc(NS(=O)(=O)c3ccc(cc3)C#N)ccc2n(C)c1=O

-20°C

12352200