Chemical Structure
Chemical Structure
NI-57
82069
CAS Number1883548-89-7
Product group Chemicals
Molecular Weight383.4 Da
Overview
- SupplierBPS Bioscience
- Product NameNI-57
- Delivery Days Customer7
- CAS Number1883548-89-7
- CertificationResearch Use Only
- Molecular FormulaC19H17N3O4
- Molecular Weight383.4 Da
- Scientific DescriptionNI-57 is a selective and potent inhibitor of BRPF (Bromodomain and PHD Finger) family of proteins (BRPF1/2/3). NI-57 shows Kd values of 31, 108 and 408 nM, for BRPF1B, 2 and 3, respectively. NI-57 also exhibits >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains. Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts.
- Storage Instruction-20°C
- UNSPSC12352200
