NIC-12 [2409826-23-7]

TargetMol Chemicals

NIC-12 [2409826-23-7]

16

Research Use Only

C22H28ClN5O2S

462.01

NIC-12, a potent NLRP3 inhibitor, selectively reduces circulating IL-1beta levels in the LPS-endotoxemia mice model and inhibits NLRP3 inflammasome activation in mouse macrophages [1].

C(C)(C)C=1N2C3=C(C=C2C(=O)N(CC(N[C@H]4CN(CC5CC5)CCC4)=O)N1)SC(Cl)=C3

-20°C

12352200