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Chemical Structure
Chemical Structure
Chemical Structure

Nicotinamide

M4896
AbMole BioScience
CAS Number98-92-0
Product group Chemicals
Estimated Purity 99.78%
Molecular Weight122.12
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Nicotinamide
  • Delivery Days Customer
    9
  • CAS Number
    98-92-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    99.78%
  • Molecular Formula
    C6H6N2O
  • Molecular Weight
    122.12
  • Scientific Description
    Nicotinamide is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins. Nicotinamide plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions.
  • SMILES
    NC(=O)C1=CC=CN=C1
  • Storage Instruction
    -20°C, protect from light, sealed
  • UNSPSC
    12352200

References

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  • Chen W, Chu J, Miao Y, et al. MOF-mediated acetylation of CDK9 promotes global transcription by modulating P-TEFb complex formation. FEBS J. 2024;291(21):4796-4812.
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  • Xiao Z, Ding L, Yu Y, et al. Tanreqing injection inhibits stemness and enhances sensitivity of non-small cell lung cancer models to gefitinib through ROS/STAT3 signaling pathway. J Cancer. 2024;15(13):4259-4274.
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  • Miao Y, Ha A, de Lau W, et al. Next-generation surrogate wnts support organoid growth and deconvolute frizzled pleiotropy in vivo. Cell Stem Cell. 2020;27(5):840-851.e6.
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  • Hasaart KAL, Manders F, van der Hoorn ML, et al. Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis. Sci Rep. 2020;10(1):12991.
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