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ProductsBack/Nicotinamide

Chemical Structure

Chemical Structure

Chemical Structure

Nicotinamide

M4896

CAS Number98-92-0

Product group Chemicals

Estimated Purity 99.78%

Molecular Weight122.12

Overview

Supplier
AbMole BioScience
Product Name
Nicotinamide
Delivery Days Customer
9
CAS Number
98-92-0
Certification
Research Use Only
Estimated Purity
99.78%
Molecular Formula
C6H6N2O
Molecular Weight
122.12
Scientific Description
Nicotinamide is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins. Nicotinamide plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions.
SMILES
NC(=O)C1=CC=CN=C1
Storage Instruction
-20°C, protect from light, sealed
UNSPSC
12352200

References

Wei D, Yuan L, Xu X, et al. Exploring epigenetic dynamics unveils a super-enhancer-mediated NDRG1-β-catenin axis in modulating gemcitabine resistance in pancreatic cancer. Cancer Lett. 2024,605:217284. doi: 10.1016/j.canlet.2024.217284
Read this paper
Chen W, Chu J, Miao Y, et al. MOF-mediated acetylation of CDK9 promotes global transcription by modulating P-TEFb complex formation. FEBS J. 2024,291(21):4796-4812. doi: 10.1111/febs.17264
Read this paper
Xiao Z, Ding L, Yu Y, et al. Tanreqing injection inhibits stemness and enhances sensitivity of non-small cell lung cancer models to gefitinib through ROS/STAT3 signaling pathway. J Cancer. 2024,15(13):4259-4274. doi: 10.7150/jca.94438
Read this paper
Miao Y, Ha A, de Lau W, et al. Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo. Cell Stem Cell. 2020,27(5):840-851.e6. doi: 10.1016/j.stem.2020.07.020
Read this paper
Hasaart KAL, Manders F, van der Hoorn ML, et al. Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis. Sci Rep. 2020,10(1):12991. doi: 10.1038/s41598-020-69822-1
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