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Niflumic acid

HY-B0493
MedChem Express
CAS Number4394-00-7
DownloadMSDS
Product group Chemicals
Estimated Purity99.88
Molecular Weight282.22
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Niflumic acid [4394-00-7]
  • Delivery Days Customer
    10
  • CAS Number
    4394-00-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.88
  • Molecular Formula
    C13H9F3N2O2
  • Molecular Weight
    282.22
  • Scientific Description
    Niflumic acid is a calcium-activated chloride channel blocker and COX-2 inhibitor with the IC50 value of 100 nM. Niflumic acid induces apoptosis through caspase-8/Bid/Bax pathway in lung cancer cells. Niflumic acide exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9. Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis[1][2][3][4][5][6][7][8].
  • SMILES
    O=C(C1=CC=CN=C1NC2=CC=CC(C(F)(F)F)=C2)O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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