NIK SMI1

MedChem Express

NIK SMI1 [1660114-31-7]

5

1660114-31-7

Research Use Only

99.95

C20H19N3O4

365.38

NIK SMI1 is a potent, selective NF-kappaB inducing kinase ( NIK ) inhibitor, which inhibits NIK-catalyzed hydrolysis of ATP to ADP with IC 50 of 0.23+/-0.17 nM. NIK SMI1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(N)C1=NC(C2=CC=CC(C#C[C@]3(O)CCN(C)C3=O)=C2)=CC(OC)=C1

-20°C,2°C to 8°C

12352200