Nimbolide

MedChem Express

Nimbolide [25990-37-8]

10

25990-37-8

Research Use Only

99.94

C27H30O7

466.52

Nimbolide is a triterpene compound that can be isolated from neem ( Azadirachta indica ), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-kappaB and CDK4 / CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways [1] [2] .

C[C@]12[C@@]3([H])[C@](OC([C@@]3(C=CC2=O)C)=O)([H])[C@]4([H])[C@]([C@@H]1CC(OC)=O)(C5=C(C)[C@@](C6=COC=C6)([H])C[C@@]5([H])O4)C

-20°C

12352200